While checkpoint inhibitors can lead to durable responses in a range of metastatic cancers, unanticipated immune-related adverse events can limit the utility of these life-saving therapies. A group of researchers led by Dr.
“We elected to characterize the samples from this patient with the GeoMx DSP because the patient tissue was limited and had been preserved in FFPE. The GeoMx platform enabled high-plex characterization that would not have been possible on other platforms,” said
“This study is the sixth peer-reviewed publication to highlight the importance of spatial profiling for characterizing mechanisms of action and toxicity of immunotherapies, which may ultimately result in improved treatment options for patients,” said
The data for this publication was generated as part of a collaboration with
The GeoMx Digital Spatial Profiler enables researchers to rapidly and quantitatively characterize tissue morphology with a high-throughput, high-plex RNA and protein profiling system that preserves samples for future analyses.
Interested parties can learn more about DSP by visiting https://www.nanostring.com/scientific-content/technology-overview/digital-spatial-profiling-technology.
For more information, please visit www.nanostring.com.
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Source: NanoString Technologies, Inc.