The combination of Bio-Techne’s RNA imaging and NanoString’s RNA spatial profiling technology creates compelling value for spatial genomics applications. The synergies in the chemistry and workflow create two key advantages. First, unlike antibodies, RNAscope reagents are universal and can image any known transcript. This enables nearly endless combinations of key transcripts that can be imaged to select regions of interest for spatial genomics profiling using GeoMx DSP. Second, GeoMx DSP offers the only high-plex RNA spatial profiling chemistry that is compatible with FFPE. By combining with Bio-Techne’s high sensitivity FFPE compatible RNAscope reagents, spatial genomics applications can be extended from basic research to translational and clinical applications.
The new partnership leverages the power of RNAscope reagents for visualizing molecular RNA targets, and GeoMx DSP data for high-plex profiling and quantification of RNA. Under the terms of the agreement,
“Understanding the tissue microenvironment at the cellular and system level enables researchers to gain insights into tissue function and mechanisms as related to normal development as well as mechanism of disease.
“This partnership brings together two best-in-class assays that enable imaging and profiling in difficult sample types like FFPE. It provides researchers with the most complete and integrated solution available for RNA biomarkers,” said
GeoMx Digital Spatial Profiling
GeoMx DSP enables high throughput multiplex spatial profiling of RNA and protein targets in a variety of sample types, including FFPE tissue sections. The full launch of the GeoMx DSP platform is scheduled to take place at the upcoming AACR meeting being held March 29 - April 3, 2019, and over 30 systems have already been pre-ordered. At AACR 2019, 13 posters will be presented featuring spatial applications using GeoMx DSP; 10 of the posters will be presented by customers, collaborators and GeoMx DSP beta sites.
About NanoString Technologies, Inc.
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Senior Vice President, Investor Relations
Vice President, Investor Relations & Corporate Communications
Source: NanoString Technologies, Inc.